Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 11/20 | 0.47 |
| ▸ | CBFB | Q13951 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902403 | 0.92 | DGAT1 (0.57) | DGAT1SOAT1KCNH2ADORA2ANPBWR1 | |
| SCHEMBL902394 | 0.84 | DGAT1 (0.65) | DGAT1SOAT1KCNH2ADORA2ANPBWR1 | |
| SCHEMBL902157 | 0.79 | DGAT1 (0.75) | DGAT1SOAT1KCNH2ADORA2ASCD | |
| SCHEMBL10189664 | 0.77 | DGAT1 (0.60) | DGAT1SOAT1KCNH2ADORA2ASCD | |
| SCHEMBL902815 | 0.72 | CBFB (0.64) | DGAT1CBFBNPBWR1SCD | |
| SCHEMBL902577 | 0.72 | DGAT1 (0.53) | DGAT1SOAT1KCNH2ADORA2A | |
| SCHEMBL10188922 | 0.71 | DGAT1 (0.41) | DGAT1SOAT1KCNH2ADORA2A | |
| SCHEMBL10189190 | 0.71 | DGAT1 (0.44) | DGAT1SOAT1KCNH2ADORA2A | |
| SCHEMBL10189564 | 0.71 | DGAT1 (0.47) | DGAT1SOAT1KCNH2 | |
| SCHEMBL901617 | 0.70 | DGAT1 (0.50) | DGAT1SOAT1KCNH2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |