Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029289 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2HPGDALDH1A1TP53MAPT | |
| SCHEMBL9029483 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2HPGDALDH1A1MMP2MMP9 | |
| SCHEMBL9029495 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2HPGDALDH1A1MMP2MMP9 | |
| SCHEMBL9308729 | 0.82 | HPGD (0.58) | HPGDALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL9030080 | 0.80 | UTS2R (0.45) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL9310714 | 0.80 | HPGD (0.62) | SMN1; SMN2HPGDALDH1A1TP53MAPT | |
| SCHEMBL9034399 | 0.76 | HPGD (0.52) | SMN1; SMN2HPGDALDH1A1TP53NPC1 | |
| SCHEMBL9309615 | 0.75 | HPGD (0.51) | SMN1; SMN2HPGDALDH1A1TP53NPC1 | |
| SCHEMBL9308546 | 0.75 | MEN1 (0.53) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL9308604 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2HPGDALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486386-B1 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR (FR) | 1996-07-17 | — | — | EP | claimed |
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | claimed |