SCHEMBL9308604

SCHEMBL9308604

O=C(O)C1CC(O)CN1C(=O)c1ccc2c(c1)OCCO2

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 4/20 0.49
HPGD P15428 4/20 0.49
RECQL P46063 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
CHRNA7 P36544 1/20 0.47
LMNA P02545 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PKM P14618 2/20 0.44
ATM Q13315 2/20 0.43
CTNNB1 P35222 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPT P10636 1/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9034399 0.92 HPGD (0.52) ALDH1A1TSHRHPGDSMN1; SMN2HSD17B10
SCHEMBL9310652 0.89 TSHR (0.51) ALDH1A1TSHRHPGDRECQLSMN1; SMN2
SCHEMBL9308546 0.85 MEN1 (0.53) ALDH1A1TSHRHPGDRECQLSMN1; SMN2
SCHEMBL9309615 0.81 HPGD (0.51) ALDH1A1TSHRHPGDSMN1; SMN2HSD17B10
SCHEMBL9310714 0.78 HPGD (0.62) ALDH1A1TSHRHPGDSMN1; SMN2LMNA
SCHEMBL9308274 0.77 KMO (0.48) TSHRHPGDPKMATM
SCHEMBL9308270 0.77 KMO (0.48) TSHRHPGDPKMATM
SCHEMBL9028119 0.76 PIK3CD (0.61) CHRNA7ATM
SCHEMBL9028110 0.76 PIK3CD (0.61) CHRNA7ATM
SCHEMBL10469223 0.76 PIK3CD (0.61) CHRNA7ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332735-A Antiamnesic activity ADIR ET COMPAGNIE (FR) 1994-07-26 US disclosed