Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029483 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2D6CYP2C9ALDH1A1KMT2A | |
| SCHEMBL9029289 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP2D6CYP2C9ALDH1A1KMT2A | |
| SCHEMBL9029299 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP2D6CYP2C9ALDH1A1KMT2A | |
| SCHEMBL9307811 | 0.82 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1KMT2AMEN1MMP2 | |
| SCHEMBL9310091 | 0.80 | ANPEP (0.64) | CYP2C9ALDH1A1KMT2AMEN1MMP2 | |
| SCHEMBL21697319 | 0.76 | MMP2 (0.50) | CYP2D6CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL9310050 | 0.76 | MMP2 (0.50) | CYP2C9ALDH1A1KMT2AMEN1MMP2 | |
| SCHEMBL9028847 | 0.76 | MMP2 (0.50) | CYP2D6CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL9029677 | 0.76 | MMP2 (0.50) | CYP2C9ALDH1A1KMT2AMEN1MMP2 | |
| SCHEMBL9028843 | 0.76 | MMP2 (0.50) | CYP2D6CYP2C9ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486386-B1 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR (FR) | 1996-07-17 | — | — | EP | claimed |
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | claimed |