Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029295 | 1.00 | L3MBTL1 (0.41) | L3MBTL1KMT2ATSHRALDH1A1MEN1 | |
| SCHEMBL14518854 | 0.92 | L3MBTL1 (0.43) | L3MBTL1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL27334084 | 0.87 | TSHR (0.40) | L3MBTL1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL1343753 | 0.87 | L3MBTL1 (0.44) | L3MBTL1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL10942498 | 0.84 | TSHR (0.38) | L3MBTL1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL27330978 | 0.82 | ALDH1A1 (0.50) | KMT2ATSHRALDH1A1MEN1KDM4E | |
| SCHEMBL14518853 | 0.82 | DPP4 (0.47) | L3MBTL1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL4344258 | 0.82 | TSHR (0.57) | L3MBTL1KMT2ATSHRALDH1A1POLB | |
| SCHEMBL1584098 | 0.81 | TSHR (0.48) | L3MBTL1KMT2ATSHRALDH1A1MEN1 | |
| SCHEMBL30317225 | 0.81 | TSHR (0.40) | L3MBTL1KMT2ATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703905-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1996-04-03 | — | — | EP | disclosed |