Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634958 | 0.86 | ADH1B (0.36) | TSHRSMN1; SMN2ACE2ADH1BADH1C | |
| SCHEMBL6061890 | 0.86 | ADH1B (0.36) | TSHRSMN1; SMN2ACE2ADH1BADH1C | |
| SCHEMBL306389 | 0.86 | TSHR (0.40) | TSHRALDH1A1ALOX15 | |
| SCHEMBL811663 | 0.84 | ADH1B (0.39) | TSHRACE2ADH1BADH1CADH1A | |
| SCHEMBL2892162 | 0.84 | TSHR (0.36) | TSHRSMN1; SMN2ACE2LMNAADH1B | |
| SCHEMBL16178853 | 0.84 | ADH1B (0.39) | TSHRACE2ADH1BADH1CADH1A | |
| SCHEMBL3898836 | 0.84 | ACE2 (0.36) | TSHRSMN1; SMN2ACE2ALDH1A1TDP1 | |
| SCHEMBL16594818 | 0.83 | TSHR (0.31) | TSHR | |
| SCHEMBL31521557 | 0.83 | LMNA (0.48) | TSHRSMN1; SMN2ACE2ALDH1A1TDP1 | |
| SCHEMBL9650202 | 0.83 | ACE2 (0.46) | TSHRSMN1; SMN2ACE2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737682-A1 | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-10-16 | — | — | EP | disclosed |