SCHEMBL9029488

SCHEMBL9029488

c1nnnc(N2CCCCC2)c1N1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.45
KEAP1 Q14145 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 5/20 0.38
GFER P55789 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 7/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 3/20 0.36
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GAA P10253 1/20 0.36
POLB P06746 2/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17784881 0.80 ALDH1A1 (0.41) HPGDKEAP1MAPK1GFERMEN1
SCHEMBL28782722 0.80 SMARCA2 (0.42) HPGDKEAP1MAPK1MEN1KMT2A
SCHEMBL16040705 0.68 KEAP1 (0.50) KEAP1MAPK1MEN1KMT2AALDH1A1
SCHEMBL5756540 0.67 ALDH1A1 (0.35) HPGDKEAP1SMN1; SMN2MAPK1MEN1
Hydrochloric Acid SCHEMBL5754916 0.66 ALDH1A1 (0.34) HPGDKEAP1SMN1; SMN2MAPK1NPC1
SCHEMBL8656365 0.65 HPGD (0.39) HPGDKEAP1SMN1; SMN2MAPK1GFER
SCHEMBL15415347 0.65 HPGD (0.39) HPGDKEAP1SMN1; SMN2MAPK1GFER
SCHEMBL5759783 0.64 NR1I2 (0.33) HPGDSMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL14815802 0.63 CNR2 (0.44) HPGDSMN1; SMN2MAPK1MEN1KMT2A
Hydrochloric Acid SCHEMBL5754089 0.63 NR1I2 (0.33) SMN1; SMN2NPC1ALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0345220-B1 Polyamines partially substituted by bis-piperidyl-triazines CIBA GEIGY AG (CH) 1996-08-28 EP disclosed
US-4981964-A PHOTOSTABILIZERS ICI AMERICAS INC. (US) 1991-01-01 US disclosed
US-4981964-A PHOTOSTABILIZERS ICI AMERICAS INC. (US) 1991-01-01 US disclosed
CN-1045103-A The oligomer ester and the oligoamide that contain the dipiperidino triazine group ICI AMERICA INC (US) 1990-09-05 CN disclosed
CN-1045103-A The oligomer ester and the oligoamide that contain the dipiperidino triazine group ICI AMERICA INC (US) 1990-09-05 CN disclosed
CN-1045103-A The oligomer ester and the oligoamide that contain the dipiperidino triazine group ICI AMERICA INC (US) 1990-09-05 CN disclosed
EP-0373839-A1 Oligomeric polyesters and polyamides containing dipiperidyl triazine groups ICI AMERICAS INC. (US) 1990-06-20 EP disclosed
EP-0373839-A1 Oligomeric polyesters and polyamides containing dipiperidyl triazine groups ICI AMERICAS INC. (US) 1990-06-20 EP disclosed
US-4933451-A LIGHT, HEAT AND OXIDATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1990-06-12 US disclosed
US-4933451-A LIGHT, HEAT AND OXIDATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1990-06-12 US disclosed
EP-0345220-A2 Polyamines partially substituted by bis-piperidyl-triazines CIBA-GEIGY AG (CH) 1989-12-06 EP disclosed
EP-0345220-A2 Polyamines partially substituted by bis-piperidyl-triazines CIBA-GEIGY AG (CH) 1989-12-06 EP disclosed