Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761337 | 1.00 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9APOLBNR1I2 | |
| Hydrochloric Acid SCHEMBL5754916 | 0.98 | ALDH1A1 (0.34) | ALDH1A1NPC1RAB9APOLBNR1I2 | |
| SCHEMBL5759783 | 0.98 | NR1I2 (0.33) | ALDH1A1NPC1RAB9APOLBNR1I2 | |
| Hydrochloric Acid SCHEMBL5754089 | 0.96 | NR1I2 (0.33) | ALDH1A1NPC1RAB9APOLBNR1I2 | |
| SCHEMBL985163 | 0.82 | ALDH1A1 (0.38) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL5759411 | 0.82 | ADRB2 (0.43) | ALDH1A1SMARCA2SMARCA4PBRM1 | |
| Hydrochloric Acid SCHEMBL5249555 | 0.81 | ALDH1A1 (0.37) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL6824239 | 0.72 | NR1I2 (0.36) | ALDH1A1NPC1POLBNR1I2SMARCA2 | |
| SCHEMBL5758464 | 0.72 | ROCK2 (0.40) | ALDH1A1NPC1POLBNR1I2SMARCA2 | |
| SCHEMBL5757261 | 0.69 | ROCK2 (0.38) | NPC1NR1I2SMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266651-B1 | UV absorbing and photostabilizing agents and compositions and external preparation for skin | SHISEIDO CO LTD (JP) | 2006-09-06 | — | — | EP | disclosed |
| US-6676932-B2 | CONTAINING PYRIDAZINE DERIVATIVE SUNSCREEN AGENT | SHISEIDO CO., LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030198608-A1 | Ultraviolet absorbent, photostabilizer, ultraviolet ray-absorbing composition, photostabilized composition and external prepraration for skin | SHISEIDO CO., LTD. (JP) | 2003-10-23 | — | — | US | disclosed |
| EP-1266651-A2 | UV absorbing and photostabilizing agents and compositions and external preparation for skin | SHISEIDO COMPANY LIMITED (JP) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030198608-A1 | Ultraviolet absorbent, photostabilizer, ultraviolet ray-absorbing composition, photostabilized composition and external prepraration for skin | SUN2, UPF1, RRM1 | ALDH1A1 2169/4885NPC1 3973/4885RAB9A 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.