Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | F7 | P08709 | 3/20 | 0.35 |
| ▸ | F3 | P13726 | 3/20 | 0.35 |
| ▸ | UBE2T | Q9NPD8 | 2/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 4/20 | 0.32 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174692 | 0.80 | F2 (0.42) | PRSS1PRSS2PRSS3F10F7 | |
| SCHEMBL9030206 | 0.74 | PRMT1 (0.32) | PRSS1PRSS2PRSS3F10F7 | |
| SCHEMBL8169531 | 0.71 | F2 (0.40) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL6706897 | 0.71 | KCNA5 (0.47) | — | |
| SCHEMBL9030472 | 0.70 | PRSS1 (0.41) | PRSS1PRSS2PRSS3F10F7 | |
| SCHEMBL9030715 | 0.70 | PRSS1 (0.51) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL18719680 | 0.69 | UBE2T (0.45) | PRSS1PRSS2PRSS3UBE2TF2 | |
| SCHEMBL9031211 | 0.68 | F10 (0.48) | PRSS1PRSS2PRSS3F10TMPRSS15 | |
| SCHEMBL6708539 | 0.68 | ATM (0.33) | — | |
| SCHEMBL9030918 | 0.68 | F2 (0.43) | PRSS1PRSS2PRSS3F10TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |