Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | C1S | P09871 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174692 | 0.78 | F2 (0.42) | PRSS1PRSS2PRSS3TMPRSS15F2 | |
| SCHEMBL9031211 | 0.75 | F10 (0.48) | PRSS1PRSS2PRSS3TMPRSS15F2 | |
| SCHEMBL9030715 | 0.74 | PRSS1 (0.51) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL9030918 | 0.74 | F2 (0.43) | PRSS1PRSS2PRSS3TMPRSS15F2 | |
| SCHEMBL7115360 | 0.72 | PPARG (0.57) | PRSS1PRSS2PRSS3TMPRSS15F2 | |
| SCHEMBL19486248 | 0.72 | PPARG (0.57) | PRSS1PRSS2PRSS3TMPRSS15F2 | |
| SCHEMBL19486255 | 0.72 | PPARG (0.57) | PRSS1PRSS2PRSS3TMPRSS15F2 | |
| SCHEMBL8169531 | 0.72 | F2 (0.40) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL9029684 | 0.70 | PRSS1 (0.37) | PRSS1PRSS2PRSS3TMPRSS15F2 | |
| SCHEMBL9030101 | 0.70 | ALDH1A1 (0.49) | PRSS1PRSS2PRSS3F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |