Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031163 | 0.89 | PPARG (0.37) | HTR2APPARGENPP2 | |
| SCHEMBL9293255 | 0.87 | HTR2A (0.30) | HTR2AHTR2C | |
| SCHEMBL9029914 | 0.83 | HTR2A (0.32) | HTR2APPARGHTR2C | |
| SCHEMBL9029437 | 0.81 | ALOX5 (0.33) | PPARG | |
| SCHEMBL9029711 | 0.80 | PPARG (0.36) | PPARG | |
| SCHEMBL9030559 | 0.80 | — | — | |
| SCHEMBL9678373 | 0.79 | HTR2A (0.32) | HTR2A | |
| SCHEMBL9029982 | 0.78 | CHEK1 (0.36) | PPARG | |
| SCHEMBL9030891 | 0.76 | PPARA (0.40) | PPARG | |
| SCHEMBL9676919 | 0.76 | PPARG (0.34) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513285-B1 | IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA SPA (IT) | 1996-01-24 | — | — | EP | disclosed |
| US-5356920-A | Anticholesterol, antilipemic agent | FARMITALIA CARLO ERBA SRL. (IT) | 1994-10-18 | — | — | US | disclosed |
| WO-1992009582-A1 | IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA SRL (IT) | 1992-06-11 | — | — | WO | disclosed |