SCHEMBL9293255

SCHEMBL9293255

CC(CCOc1ccc2c(c1)C=C(c1nccn1C)C(CCc1ccc(F)cc1F)O2)C(C)(C)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9031163 0.89 PPARG (0.37) HTR2A
SCHEMBL9029922 0.87 HTR2A (0.34) HTR2AHTR2C
SCHEMBL9029914 0.84 HTR2A (0.32) HTR2AHTR2C
SCHEMBL9678373 0.82 HTR2A (0.32) HTR2A
SCHEMBL9029711 0.80 PPARG (0.36)
SCHEMBL9030229 0.77 TBXAS1 (0.34)
SCHEMBL9029885 0.76 PPARG (0.32)
SCHEMBL9031371 0.76 ALOX5 (0.38)
SCHEMBL9030323 0.75 HCRTR2 (0.33)
SCHEMBL10372672 0.75 ALOX5 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5356920-A Anticholesterol, antilipemic agent FARMITALIA CARLO ERBA SRL. (IT) 1994-10-18 US disclosed
WO-1992009582-A1 IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION FARMITALIA CARLO ERBA SRL (IT) 1992-06-11 WO disclosed