Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262033 | 0.90 | AGTR1 (0.38) | AGTR1AGTR2ALDH1A1TDP1 | |
| SCHEMBL9033410 | 0.89 | AGTR1 (0.40) | AGTR1AGTR2ALDH1A1TDP1 | |
| SCHEMBL9031955 | 0.89 | AGTR1 (0.39) | AGTR1AGTR2ALDH1A1TDP1 | |
| SCHEMBL9031320 | 0.88 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9031512 | 0.87 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9032855 | 0.87 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9029855 | 0.86 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9032292 | 0.86 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9030859 | 0.86 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9032973 | 0.86 | AGTR1 (0.41) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483683-B1 | Thienoimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5463073-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0483683-A2 | Thienoimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-06 | — | — | EP | disclosed |