Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 6/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030884 | 0.82 | PNP (0.57) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL9029804 | 0.82 | PDE4A (0.58) | ADORA3ADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL9030966 | 0.80 | PDE4A (0.55) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9032044 | 0.78 | PDE4A (0.56) | ADORA3ADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL3107001 | 0.74 | ADORA3 (0.78) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL9029959 | 0.72 | PDE4A (0.54) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9030681 | 0.71 | HPGD (0.51) | ADORA2BKMT2APOLBKDM4E | |
| SCHEMBL9119046 | 0.71 | ADORA2B (0.81) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL9030631 | 0.71 | ADORA2B (0.46) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9032111 | 0.69 | PNP (1.00) | PNPADORA3ADORA2BPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417790-B1 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-12-04 | — | — | EP | claimed |
| US-5173492-A | Bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-12-22 | — | — | US | claimed |
| EP-0417790-B1 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5173492-A | Bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-12-22 | — | — | US | disclosed |