Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177377 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1IDO1SLC6A4TUBB4A | |
| SCHEMBL9176380 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1IDO1SLC6A4TUBB4A | |
| SCHEMBL9030645 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1IDO1SLC6A4TUBB4A | |
| SCHEMBL9172463 | 0.85 | ALDH1A1 (0.46) | SMN1; SMN2L3MBTL1IDO1SLC6A4TUBB4A | |
| SCHEMBL9172798 | 0.83 | SLC6A4 (0.46) | IDO1SLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL9031186 | 0.80 | GABRA1 (0.48) | SMN1; SMN2MAPTMEN1GAAKMT2A | |
| SCHEMBL9176461 | 0.80 | IDO1 (0.42) | SMN1; SMN2L3MBTL1IDO1SLC6A4TUBB4A | |
| SCHEMBL9038086 | 0.80 | IDO1 (0.42) | SMN1; SMN2L3MBTL1IDO1SLC6A4TUBB4A | |
| SCHEMBL9178346 | 0.80 | IDO1 (0.47) | SMN1; SMN2L3MBTL1IDO1SLC6A4TUBB4A | |
| SCHEMBL9174233 | 0.79 | MAPT (0.39) | SMN1; SMN2L3MBTL1IDO1SLC6A4TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708104-B1 | Process and intermediate for the preparation of terazosin hydrochloride dihydrate | ABBOTT LAB (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0699195-A1 | THIOINDOLE PYPERIDINYL DERIVATIVES USED AS ANTALGICS | LABORATOIRES UPSA (FR) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994026736-A1 | THIOINDOLE PYPERIDINYL DERIVATIVES USED AS ANTALGICS | LABORATOIRES UPSA (FR) | 1994-11-24 | — | — | WO | disclosed |