Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172798 | 0.86 | SLC6A4 (0.46) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9177126 | 0.85 | IDO1 (0.48) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9176461 | 0.83 | IDO1 (0.42) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9172463 | 0.81 | ALDH1A1 (0.46) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9038086 | 0.81 | IDO1 (0.42) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9029972 | 0.80 | SMN1; SMN2 (0.46) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9030645 | 0.80 | SMN1; SMN2 (0.41) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9176697 | 0.79 | SLC6A4 (0.57) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9176380 | 0.79 | SMN1; SMN2 (0.44) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9031186 | 0.79 | GABRA1 (0.48) | MAPTMEN1GAAKMT2ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418242-A | Piperidinylthioindole derivatives, their methods of preparation and pharmaceutical compositions in which they are present, useful especially as analgesics | LABORATOIRES UPSA (FR) | 1995-05-23 | — | — | US | disclosed |