Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3185213 | 0.85 | TSHR (0.40) | TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL27501999 | 0.82 | FAAH (0.47) | KMT2AMEN1LMNAALDH1A1HSD17B10 | |
| SCHEMBL4770469 | 0.82 | TSHR (0.48) | TSHRKMT2ALMNAALDH1A1 | |
| SCHEMBL23723861 | 0.81 | TSHR (0.35) | TSHRKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL22605826 | 0.80 | ALDH1A1 (0.38) | TSHRKMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL6618945 | 0.80 | FAAH (0.55) | KMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL5769222 | 0.79 | CAMK2A (0.37) | TSHRALDH1A1 | |
| SCHEMBL16540471 | 0.79 | TSHR (0.65) | TSHRKMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL10499113 | 0.78 | FAAH (0.57) | KMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL11293992 | 0.78 | FAAH (0.57) | KMT2AMEN1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | disclosed |
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |