Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920526 | 0.84 | MEN1 (0.35) | MEN1ALDH1A1KMT2ATDP1NOTUM | |
| SCHEMBL9340518 | 0.84 | NOTUM (0.39) | MEN1ALDH1A1KMT2ATDP1NOTUM | |
| SCHEMBL10482195 | 0.77 | KDR (0.35) | ALDH1A1TDP1NOTUMKDR | |
| SCHEMBL9344674 | 0.76 | NOTUM (0.38) | MEN1ALDH1A1KMT2ATDP1NOTUM | |
| SCHEMBL9344684 | 0.76 | ALDH1A1 (0.45) | MEN1ALDH1A1KMT2ATDP1NOTUM | |
| SCHEMBL9340504 | 0.74 | KIF11 (0.35) | MEN1ALDH1A1KMT2ATDP1KIF11 | |
| SCHEMBL29560171 | 0.74 | KIF11 (0.35) | MEN1ALDH1A1KMT2ATDP1NOTUM | |
| SCHEMBL9340556 | 0.74 | KIF11 (0.35) | MEN1ALDH1A1KMT2ATDP1NOTUM | |
| SCHEMBL9342580 | 0.73 | ERN1 (0.34) | TDP1NOTUMKIF11KDR | |
| SCHEMBL1312706 | 0.73 | CYP3A4 (0.50) | MEN1ALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538301-B1 | HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1996-10-30 | — | — | EP | disclosed |
| US-5556886-A | VIRICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-09-17 | — | — | US | disclosed |
| EP-0396987-B1 | Nuclear fluorinated trifluoromethylbenzaldehydes | BAYER AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| EP-0538301-A1 | HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES. | JANSSEN PHARMACEUTICA NV (BE) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000952-A1 | HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-01-23 | — | — | WO | disclosed |
| US-5041683-A | Nuclear-fluorinated trifluoromethylbenzaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |
| EP-0396987-A2 | Nuclear fluorinated trifluoromethylbenzaldehydes | BAYER AG (DE) | 1990-11-14 | — | — | EP | disclosed |