Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.44 |
| ▸ | HRH2 | P25021 | 4/20 | 0.40 |
| ▸ | HRH1 | P35367 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030280 | 0.88 | TP53 (0.51) | GPR119HRH2HRH1HPGDTP53 | |
| SCHEMBL9030418 | 0.86 | HRH2 (0.42) | HRH2HRH1HPGDTP53PDE4D | |
| SCHEMBL9031070 | 0.85 | GPR119 (0.45) | GPR119HRH2HRH1HPGDPDE4A | |
| SCHEMBL7680850 | 0.77 | TP53 (0.43) | GPR119TP53 | |
| SCHEMBL7687431 | 0.77 | GPR119 (0.44) | GPR119HPGDTP53 | |
| SCHEMBL7680139 | 0.77 | HRH2 (0.42) | GPR119HRH2HRH1HPGDCYP2D6 | |
| SCHEMBL7684996 | 0.77 | GAA (0.42) | GPR119HRH2HRH1SIRT3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7680696 | 0.76 | HRH2 (0.43) | HRH2HRH1HPGDPDE4DCYP2D6 | |
| SCHEMBL7837219 | 0.75 | HRH2 (0.40) | GPR119HRH2HRH1HPGDCYP2D6 | |
| Hydrochloric Acid SCHEMBL9031173 | 0.75 | TP53 (0.44) | HRH2HRH1HPGDTP53PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721941-A1 | NOVEL COMPOUND HAVING PLATELET AGGREGATION INHIBITOR EFFECT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1996-07-17 | — | — | EP | disclosed |