Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680850 | 0.87 | TP53 (0.43) | GPR119TP53KDM4EALDH1A1 | |
| SCHEMBL7677721 | 0.86 | GPR119 (0.36) | GPR119ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7677838 | 0.86 | L3MBTL1 (0.33) | MAPTKMT2AL3MBTL1 | |
| SCHEMBL7687050 | 0.81 | CYP2D6 (0.41) | MAPTKDM4EALDH1A1GAATSHR | |
| SCHEMBL7681879 | 0.81 | CYP2D6 (0.38) | MAPTKDM4EALDH1A1GAATSHR | |
| Hydrochloric Acid SCHEMBL7684461 | 0.81 | CYP2D6 (0.38) | MAPTKDM4EALDH1A1GAATSHR | |
| SCHEMBL7680107 | 0.80 | GAA (0.38) | MAPTKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL7676228 | 0.80 | CYP2D6 (0.40) | MAPTKDM4EALDH1A1GAATSHR | |
| SCHEMBL7684996 | 0.80 | GAA (0.42) | GPR119MAPTALDH1A1GAAKMT2A | |
| SCHEMBL7677688 | 0.79 | CYP2D6 (0.35) | GPR119MAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472397-B1 | Nitrogen-containing heterocyclic compounds having antiplatelet aggregation effect and medicinal use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| EP-1070712-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS HAVING ANTIPLATELET AGGREGATION EFFECT AND MEDICINAL USE THEREOF | MEIJI SEIKA KAISHA LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |