Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.58 |
| ▸ | F10 | P00742 | 5/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 6/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.44 |
| ▸ | ITGAM | P11215 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671928 | 0.79 | MIF (0.45) | F2F10PRSS1MIFHDAC6 | |
| SCHEMBL21706040 | 0.67 | F2 (0.64) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL7373045 | 0.65 | MIF (0.72) | F2F10PRSS1MIFITGB3 | |
| SCHEMBL7372374 | 0.65 | MIF (0.72) | F2F10PRSS1MIFITGB3 | |
| SCHEMBL399197 | 0.65 | KIF11 (0.48) | F2PRSS1NPC1SMN1; SMN2 | |
| SCHEMBL3989192 | 0.63 | MIF (0.45) | F2F10PRSS1MIFNPC1 | |
| SCHEMBL14183673 | 0.63 | MIF (0.58) | F2F10PRSS1MIFITGB3 | |
| SCHEMBL1446332 | 0.63 | KMT2A (0.39) | F2PRSS1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1445800 | 0.63 | PRSS1 (0.39) | F2PRSS1 | |
| SCHEMBL14214320 | 0.62 | ALDH1A1 (0.47) | MIFSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | claimed |