Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029852 | 0.82 | HRH3 (0.52) | HRH3SIGMAR1CCR3CARM1PRMT6 | |
| SCHEMBL9029620 | 0.80 | HRH3 (0.52) | HRH3SIGMAR1CCR3CARM1PRMT6 | |
| SCHEMBL9031203 | 0.79 | POLB (0.52) | GRIN2B | |
| SCHEMBL83059 | 0.77 | SIGMAR1 (0.69) | HRH3SIGMAR1CCR3CARM1PRMT6 | |
| SCHEMBL9029989 | 0.76 | HDAC3 (0.53) | GRIN2B | |
| SCHEMBL9031224 | 0.76 | SIGMAR1 (0.57) | HRH3SIGMAR1CCR3CARM1PRMT6 | |
| SCHEMBL8540740 | 0.76 | HRH3 (0.53) | HRH3SIGMAR1CCR3CARM1PRMT6 | |
| SCHEMBL10144381 | 0.76 | DAO (0.44) | HRH3 | |
| SCHEMBL9031996 | 0.76 | DRD2 (0.49) | HRH3SIGMAR1CCR3CARM1PRMT6 | |
| SCHEMBL7449796 | 0.74 | SIGMAR1 (0.74) | HRH3SIGMAR1CCR3CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |