Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.69 |
| ▸ | CCR3 | P51677 | 2/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.60 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.60 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449796 | 0.97 | SIGMAR1 (0.74) | SIGMAR1CCR3HRH3MEN1TP53 | |
| SCHEMBL7437079 | 0.95 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| SCHEMBL7444256 | 0.95 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| SCHEMBL7449513 | 0.95 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| SCHEMBL7444410 | 0.95 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| Hydrochloric Acid SCHEMBL7451916 | 0.95 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| SCHEMBL7446629 | 0.95 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| Hydrochloric Acid SCHEMBL7444207 | 0.94 | SIGMAR1 (0.70) | SIGMAR1CCR3HRH3MEN1TP53 | |
| Hydrochloric Acid SCHEMBL7456022 | 0.94 | SIGMAR1 (0.70) | SIGMAR1CCR3HRH3MEN1TP53 | |
| Hydrochloric Acid SCHEMBL7435678 | 0.94 | SIGMAR1 (0.70) | SIGMAR1CCR3HRH3MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267770-A1 | PIPERIDINE DERIVATIVES AND COSMETIC COMPOSITIONS THEREOF | L'OREAL (FR) | 2010-10-21 | — | — | US | claimed |
| US-8129409-B2 | Piperidine derivatives and cosmetic compositions thereof | L'OREAL (FR) | 2012-03-06 | — | — | US | disclosed |
| US-8129409-B2 | Piperidine derivatives and cosmetic compositions thereof | L'OREAL (FR) | 2012-03-06 | — | — | US | disclosed |
| US-20100267770-A1 | PIPERIDINE DERIVATIVES AND COSMETIC COMPOSITIONS THEREOF | L'OREAL (FR) | 2010-10-21 | — | — | US | disclosed |
| US-20100267770-A1 | PIPERIDINE DERIVATIVES AND COSMETIC COMPOSITIONS THEREOF | L'OREAL (FR) | 2010-10-21 | — | — | US | disclosed |
| US-7807695-B2 | Cosmetic use of piperidine derivatives | L'OREAL (FR) | 2010-10-05 | — | — | US | disclosed |
| US-7807695-B2 | Cosmetic use of piperidine derivatives | L'OREAL (FR) | 2010-10-05 | — | — | US | disclosed |
| EP-1758858-B1 | COSMETIC USE OF PIPERIDINE DERIVATIVES | OREAL (FR) | 2010-01-20 | — | — | EP | disclosed |
| US-20080090866-A1 | Cosmetic Use of Piperidine Derivatives | L'OREAL (FR) | 2008-04-17 | — | — | US | disclosed |
| US-20080090866-A1 | Cosmetic Use of Piperidine Derivatives | L'OREAL (FR) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267770-A1 | PIPERIDINE DERIVATIVES AND COSMETIC COMPOSITIONS THEREOF | TRPA1, PLIN5, SRM | SIGMAR1 647/4885CCR3 1911/4885HRH3 1146/4885 |
| US-20080090866-A1 | Cosmetic Use of Piperidine Derivatives | TRPA1, TRPV5, CUTA | SIGMAR1 2511/4885CCR3 3586/4885HRH3 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.