Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032203 | 0.96 | HTR1D (0.49) | HTR1DHTR1BPARP1DRD2SIGMAR1 | |
| SCHEMBL9030293 | 0.92 | HTR1D (0.52) | HTR1DHTR1BPARP1DRD2HTR1A | |
| SCHEMBL9031902 | 0.87 | HTR1D (0.50) | HTR1DHTR1BPARP1DRD2SIGMAR1 | |
| SCHEMBL9031252 | 0.86 | HTR1D (0.55) | HTR1DHTR1BPARP1DRD2HTR1A | |
| SCHEMBL9032384 | 0.86 | DRD2 (0.49) | PARP1DRD2SIGMAR1HTR1A | |
| SCHEMBL9031016 | 0.84 | DRD2 (0.47) | HTR1DHTR1BPARP1DRD2SIGMAR1 | |
| SCHEMBL9030731 | 0.83 | KDM4E (0.49) | PARP1DRD2HTR1A | |
| SCHEMBL9175703 | 0.82 | DRD2 (0.46) | HTR1DHTR1BPARP1DRD2SIGMAR1 | |
| SCHEMBL7957307 | 0.81 | HTR1D (0.51) | HTR1DHTR1BPARP1DRD2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9868303 | 0.80 | SIGMAR1 (0.59) | DRD2SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735024-A1 | Antidepressant N-(Heteroarylaminoalkyl)-4-napthyl substituted piperidines and tetrahydroperidines | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5472966-A | Antiserotonin agents; side effect reduction | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-12-05 | — | — | US | disclosed |