Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032771 | 0.83 | PPARG (0.43) | PPARGAGTR1AGTR2 | |
| SCHEMBL9033373 | 0.83 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9030796 | 0.82 | PPARG (0.44) | PPARGAGTR1AGTR2 | |
| SCHEMBL9033453 | 0.82 | PPARG (0.43) | PPARGAGTR1AGTR2 | |
| SCHEMBL9032562 | 0.82 | PPARG (0.44) | PPARGAGTR1AGTR2 | |
| SCHEMBL1417546 | 0.82 | AGTR1 (0.61) | PPARGAGTR1AGTR2 | |
| SCHEMBL9032906 | 0.81 | PPARG (0.43) | PPARGAGTR1AGTR2 | |
| SCHEMBL9031469 | 0.80 | PPARG (0.43) | PPARGAGTR1AGTR2 | |
| SCHEMBL9032306 | 0.80 | PPARG (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL9031954 | 0.79 | PPARG (0.45) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483683-B1 | Thienoimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5463073-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0483683-A2 | Thienoimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-06 | — | — | EP | disclosed |