Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514697 | 0.83 | HRH3 (0.47) | HRH3SLC6A4HRH4CACNA1H | |
| SCHEMBL9031193 | 0.72 | HRH3 (0.41) | HRH3SLC6A4CACNA1HNMT1BRD4 | |
| SCHEMBL3029004 | 0.72 | HRH4 (0.34) | HRH3SLC6A4HRH4BRD4 | |
| SCHEMBL9029989 | 0.71 | HDAC3 (0.53) | — | |
| SCHEMBL9031973 | 0.71 | HRH3 (0.46) | HRH3SLC6A4HRH4CACNA1HBRD4 | |
| SCHEMBL542826 | 0.70 | — | — | |
| SCHEMBL4122501 | 0.70 | — | — | |
| SCHEMBL9030941 | 0.70 | HRH3 (0.55) | HRH3 | |
| SCHEMBL8572531 | 0.70 | HRH3 (0.49) | HRH3SLC6A4HRH4 | |
| Methane SCHEMBL28186517 | 0.69 | GLA (0.34) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |