Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24228552 | 0.83 | HRH3 (0.44) | HRH3SLC6A4HRH4KDM1ACACNA1H | |
| SCHEMBL9031193 | 0.72 | HRH3 (0.41) | HRH3SLC6A4BRD4CACNA1H | |
| SCHEMBL20204729 | 0.72 | POLB (0.37) | HRH3BRD4GABRA1GABRG2GABRB3 | |
| SCHEMBL9031824 | 0.71 | HRH3 (0.50) | HRH3SLC6A4BRD4HRH4CACNA1H | |
| SCHEMBL8572531 | 0.70 | HRH3 (0.49) | HRH3SLC6A4HRH4FAAH | |
| SCHEMBL27381818 | 0.70 | HRH3 (0.45) | HRH3SLC6A4BRD4EP300KDM1A | |
| SCHEMBL20201744 | 0.69 | PDE9A (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8489672 | 0.67 | HPGDS (0.48) | HRH3GABRA1HRH4 | |
| SCHEMBL28184865 | 0.67 | HRH3 (0.42) | HRH3SLC6A4BRD4KDM1A | |
| SCHEMBL28184146 | 0.67 | LMNA (0.45) | HRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |