Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 2/20 | 0.72 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15245075 | 0.99 | RHEB (0.70) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL3333407 | 0.91 | RHEB (0.68) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL20982583 | 0.88 | RHEB (0.70) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL9032997 | 0.87 | ALDH1A1 (0.62) | RHEBKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL15245088 | 0.86 | RHEB (0.55) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL3335014 | 0.86 | ALDH1A1 (0.61) | RHEBKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL20535350 | 0.84 | RHEB (1.00) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL1662876 | 0.82 | RHEB (0.63) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL3341423 | 0.82 | PKN1 (0.72) | RHEBDGAT1SOAT1KCNH2PKN1 | |
| SCHEMBL15245087 | 0.80 | CYP11B2 (0.52) | RHEBDGAT1SOAT1KCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511187-B1 | Process for the preparation of 1H-benzimidazoles | UCB SA (BE) | 1996-11-20 | — | — | EP | disclosed |
| EP-0511187-A1 | Process for the preparation of 1H-benzimidazoles | U C B, S.A. (BE) | 1992-10-28 | — | — | EP | disclosed |