Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035315 | 1.00 | OXER1 (0.43) | OXER1PLA2G4AS1PR1PPARGNR1H2 | |
| SCHEMBL9034115 | 0.95 | PPARG (0.41) | OXER1PLA2G4AS1PR1PPARGNR1H2 | |
| SCHEMBL9033787 | 0.91 | RORC (0.39) | OXER1PLA2G4APPARGNR1H2PPARD | |
| SCHEMBL9034842 | 0.85 | ACACB (0.39) | PPARGNR1H2PPARDPPARANR1H3 | |
| SCHEMBL9032816 | 0.84 | PLA2G4A (0.43) | OXER1PLA2G4AS1PR1KCNQ3KCNQ2 | |
| SCHEMBL9032237 | 0.83 | HCAR3 (0.38) | PPARGNR1H2PPARDPPARANR1H3 | |
| SCHEMBL9035312 | 0.81 | PLG (0.49) | PLA2G4APLGPLAU | |
| SCHEMBL9032982 | 0.81 | PLG (0.49) | PLA2G4APLGPLAU | |
| SCHEMBL9035319 | 0.81 | PLG (0.49) | PLA2G4APLGPLAU | |
| SCHEMBL9032967 | 0.81 | PLG (0.49) | PLA2G4APLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511477-B1 | Indole derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5239083-A | Anticarcinogenic agents, prostate cancer treatment | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0511477-A1 | Indole derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |