Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870228 | 1.00 | LMNA (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL17877722 | 0.84 | TSHR (0.44) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL17869143 | 0.83 | TSHR (0.42) | MAOBL3MBTL1MAPTMAOARAB9A | |
| SCHEMBL6257616 | 0.81 | AKT2 (0.59) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL13373563 | 0.81 | LMNA (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL17713692 | 0.80 | APP (0.54) | MAOBMAPTRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL4051954 | 0.77 | AKT1 (0.54) | MAOBMAPTMAOAPRMT5BCHE | |
| SCHEMBL1365650 | 0.74 | L3MBTL1 (0.58) | MAOBL3MBTL1MAPTMAOARAB9A | |
| SCHEMBL339813 | 0.74 | LMNA (0.82) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| Benzylphenylether SCHEMBL61660 | 0.74 | LMNA (0.74) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108371662-A | A kind of application of five-ring heterocycles miazines compound | 中国药科大学 | 2018-08-07 | — | — | CN | claimed |
| EP-0483851-B1 | Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives | MITSUBISHI CHEM CORP (JP) | 1996-03-13 | — | — | EP | claimed |
| EP-0483851-A1 | Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives | Mitsubishi Chemical Corporation (JP) | 1992-05-06 | — | — | EP | claimed |
| US-20240389593-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-11-28 | — | — | US | disclosed |
| EP-4317160-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | Kumiai Chemical Industry Co., Ltd. (JP) | 2024-02-07 | — | — | EP | disclosed |
| CN-117098759-A | Heterocyclic compounds and their use | 组合化学工业株式会社 | 2023-11-21 | — | — | CN | disclosed |
| WO-2022210999-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | クミアイ化学工業株式会社 | 2022-10-06 | — | — | WO | disclosed |
| WO-2021085370-A1 | AZOLE DERIVATIVE AND USE THEREOF | クミアイ化学工業株式会社 | 2021-05-06 | — | — | WO | disclosed |
| CN-108658976-B | Novel pyrazolo [4,3-c ] pyridine-4 (5) -ketone Bruton kinase inhibitor | 南京科技职业学院 | 2021-02-19 | — | — | CN | disclosed |
| CN-108371662-A | A kind of application of five-ring heterocycles miazines compound | 中国药科大学 | 2018-08-07 | — | — | CN | disclosed |
| CN-105121444-B | Cyano ethyl Pyrazolopyridine ketone as the other than ring type of JANUS kinase inhibitors | 默沙东公司 | 2018-02-16 | — | — | CN | disclosed |
| EP-3209296-A1 | ETHYL N-BOC PIPERIDINYL PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-08-30 | — | — | EP | disclosed |
| CN-107106547-A | Ethyl N-Boc piperidinyl pyrazolopyridinones as Janus kinase inhibitors | 默沙东公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-106029661-A | Pyrazolo [1,5-A ] pyridine derivatives and methods of use thereof | 亚尼塔公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105121444-A | Acyclic cyanoethylpyrazolo pyridones as JANUS kinase inhibitors | MERCK SHARP & DOHME | 2015-12-02 | — | — | CN | disclosed |
| US-3979409-A | DEHYDROGENATION WITH N-BROMO OR N-CHLORO-SUCCINIMIDE | AMERICAN CYANAMID COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3979409-A | DEHYDROGENATION WITH N-BROMO OR N-CHLORO-SUCCINIMIDE | AMERICAN CYANAMID COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240389593-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | C1S, C3AR1, CBR3 | LMNA 2764/4885CYP1A2 300/4885PTGS1 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.