Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819620 | 0.80 | DRD4 (0.40) | DRD4HTR7SIGMAR1TMEM97 | |
| SCHEMBL8193386 | 0.78 | ABCB1 (0.44) | DRD4HTR7SIGMAR1TMEM97DRD2 | |
| SCHEMBL7809525 | 0.74 | DRD4 (0.42) | DRD4HTR7SIGMAR1TMEM97 | |
| SCHEMBL7822680 | 0.72 | ABCB1 (0.41) | HTR7SIGMAR1TMEM97DRD2DRD3 | |
| SCHEMBL5539548 | 0.68 | SIGMAR1 (0.79) | DRD4HTR7SIGMAR1OPRM1DRD2 | |
| SCHEMBL5537398 | 0.67 | SIGMAR1 (0.80) | DRD4HTR7SIGMAR1OPRM1DRD2 | |
| SCHEMBL7817734 | 0.66 | HTR7 (0.44) | DRD4HTR7SIGMAR1TMEM97DRD2 | |
| SCHEMBL5535823 | 0.66 | SIGMAR1 (0.78) | DRD4HTR7SIGMAR1OPRM1DRD2 | |
| SCHEMBL5544276 | 0.66 | SIGMAR1 (0.78) | DRD4HTR7SIGMAR1OPRM1DRD2 | |
| SCHEMBL7994710 | 0.66 | HTR7 (0.41) | DRD4HTR7DRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749971-A1 | Thiopyran derivatives | SUNTORY LIMITED (JP) | 1996-12-27 | — | — | EP | disclosed |