Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 9/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033787 | 0.84 | RORC (0.39) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL9034115 | 0.82 | PPARG (0.41) | — | |
| SCHEMBL5094204 | 0.82 | KDM4E (0.58) | CYP2A6FAAHCACNA1HCHRNA7PRKCI | |
| SCHEMBL9465516 | 0.81 | KDM4E (0.33) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL9032878 | 0.81 | HDAC8 (0.51) | — | |
| SCHEMBL9032949 | 0.81 | HTR2C (0.39) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL9039376 | 0.81 | ICMT (0.37) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL9032667 | 0.81 | KCNQ3 (0.38) | — | |
| SCHEMBL9032977 | 0.80 | OXER1 (0.43) | — | |
| SCHEMBL9035315 | 0.80 | OXER1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511477-B1 | Indole derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5239083-A | Anticarcinogenic agents, prostate cancer treatment | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0511477-A1 | Indole derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |