Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | APP | P05067 | 1/20 | 0.68 |
| ▸ | SNCA | P37840 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033307 | 0.93 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL20445410 | 0.88 | KDM4E (0.68) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL20445296 | 0.88 | NPC1 (0.60) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL3335014 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL8396715 | 0.86 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL16281922 | 0.85 | NPC1 (0.66) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL9032997 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL5595593 | 0.84 | MEN1 (0.71) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL419961 | 0.84 | MEN1 (0.77) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| Ridinilazole SCHEMBL17867397 | 0.84 | NPC1 (0.65) | ALDH1A1MEN1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | claimed |