SCHEMBL9033498

SCHEMBL9033498

Cn1cc(S(=O)(=O)O)nc1F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2702033 0.77 TDP1 (0.45) PTGDR2
Hydrochloric Acid SCHEMBL27570535 0.75 TDP1 (0.44) PTGDR2
SCHEMBL3461399 0.73 PTGS2 (0.40) PTGDR2
SCHEMBL15193798 0.68 PIK3CG (0.38)
SCHEMBL22198973 0.66
SCHEMBL304175 0.64 LMNA (0.46)
SCHEMBL27833603 0.62 POLB (0.34)
Hydrochloric Acid SCHEMBL28056378 0.62 KAT6A (0.33)
Hydrochloric Acid SCHEMBL27398725 0.62 LMNA (0.45)
Hydrochloric Acid SCHEMBL27698205 0.61 TSHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442348-B1 Imidazole compounds, process for preparation, medicaments based on these compounds and some intermediates HOECHST AG (DE) 1996-07-17 EP disclosed
US-5356922-A Treatment of disturbances in microcirculation HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-18 US disclosed
US-5232922-A Cardiovascular disorders HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-03 US disclosed
EP-0442348-A2 Imidazole compounds, process for preparation, medicaments based on these compounds and some intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-21 EP disclosed
CN-1053919-A New imidazolium compounds, its preparation method and based on medicament and some intermediate product of these compounds HOECHST AG (DE) 1991-08-21 CN disclosed