Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460793 | 0.86 | PTGS2 (0.39) | PTGS2PTGS1GABRA2GABRB2ALDH1A1 | |
| SCHEMBL9033498 | 0.73 | PTGDR2 (0.31) | PTGDR2 | |
| SCHEMBL2702033 | 0.71 | TDP1 (0.45) | PTGDR2KDM4E | |
| Hydrochloric Acid SCHEMBL27570535 | 0.70 | TDP1 (0.44) | PTGDR2KDM4E | |
| SCHEMBL7228713 | 0.66 | MAPK13 (0.50) | PTGS2PTGS1ALDH1A1NPC1RAB9A | |
| SCHEMBL724186 | 0.65 | MAPT (0.46) | GABRA2GABRB2ALDH1A1NPC1KDM4E | |
| SCHEMBL14077066 | 0.63 | RAB9A (0.50) | ALDH1A1NPC1RAB9AALDH1A3KDM4E | |
| SCHEMBL2752103 | 0.63 | LMNA (0.52) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL1544768 | 0.62 | PTGS2 (0.47) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL1294413 | 0.62 | SCN9A (0.36) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146236-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORP. (FI) | 2010-12-23 | — | — | WO | disclosed |