Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201113 | 0.75 | PIK3CA (0.47) | MAPK1 | |
| SCHEMBL5029586 | 0.72 | GRM5 (0.51) | GRM5KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9413728 | 0.71 | MEN1 (0.55) | GRM5KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL13362749 | 0.71 | PIM1 (0.50) | KDM4EALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL10463825 | 0.69 | NR3C2 (0.44) | PEPDGRM5KDM4EALDH1A1KMT2A | |
| SCHEMBL10263801 | 0.69 | EP300 (0.41) | — | |
| SCHEMBL10201100 | 0.68 | HCAR3 (0.39) | KDM4EKMT2AMEN1HSD17B10GAA | |
| SCHEMBL8104147 | 0.68 | RAB9A (0.58) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2360527 | 0.67 | NPC1 (0.65) | KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL7947652 | 0.67 | HCAR3 (0.41) | ALDH1A1KMT2AMEN1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706514-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995006034-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1995-03-02 | — | — | WO | disclosed |