Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | IGF1R | P08069 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063146 | 0.88 | ALOX15 (0.63) | ALOX15HPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL27701421 | 0.87 | ALOX15 (0.61) | ALOX15HPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL396614 | 0.81 | HPGD (0.64) | ALOX15HPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30065410 | 0.81 | HPGD (0.64) | ALOX15HPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL28611035 | 0.79 | HPGD (0.62) | ALOX15HPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL27467736 | 0.79 | ALOX15 (0.77) | ALOX15HPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4274235 | 0.77 | ALDH1A1 (0.53) | ALOX15HPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL376962 | 0.76 | ALOX15 (0.47) | ALOX15HPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL297225 | 0.75 | ALOX15 (1.00) | ALOX15HPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10202005 | 0.74 | ALOX15 (0.79) | ALOX15HPGDLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |