Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266611 | 0.89 | TPMT (0.54) | TSHRALDH1A1TPMTPRSS1PRSS2 | |
| SCHEMBL14225090 | 0.85 | KDM4E (0.38) | ALDH1A1KMT2ANPC1KDM4ETDP1 | |
| SCHEMBL12837765 | 0.85 | KDM4E (0.42) | ALDH1A1KMT2ANPC1KDM4ETDP1 | |
| Glycolic Acid SCHEMBL9282210 | 0.79 | ALDH1A1 (0.57) | TSHRALDH1A1TPMTPRSS1PRSS2 | |
| SCHEMBL7194390 | 0.79 | ALDH1A1 (0.57) | TSHRALDH1A1TPMTPRSS1PRSS2 | |
| SCHEMBL12937368 | 0.78 | KDM4E (0.44) | TSHRALDH1A1TPMTKMT2AMAPT | |
| SCHEMBL27633372 | 0.78 | TPMT (0.41) | TPMTKMT2AMAPTHCAR1HPGD | |
| SCHEMBL9753152 | 0.78 | HCAR1 (0.61) | ALDH1A1TPMTKMT2AMAPTHCAR1 | |
| SCHEMBL6175987 | 0.78 | TPMT (0.64) | ALDH1A1TPMTKMT2AMAPTHCAR1 | |
| SCHEMBL11067897 | 0.77 | NPC1 (0.36) | TSHRALDH1A1GAAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485984-B1 | Diarylmethoxypiperidine derivatives | UBE INDUSTRIES (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5225559-A | DIARYLMETHOXYPIPERIDINE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0485984-A2 | Diarylmethoxypiperidine derivatives | UBE INDUSTRIES, LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |