Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369166 | 0.94 | LTA4H (0.48) | GAALTA4HTDP1L3MBTL1THRB | |
| SCHEMBL6594125 | 0.87 | MAPT (0.51) | GAALTA4HTDP1L3MBTL1THRB | |
| SCHEMBL29213722 | 0.82 | TDP1 (0.64) | TDP1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL8159189 | 0.81 | GAA (0.58) | GAATDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL3267158 | 0.81 | TDP1 (0.51) | LTA4HTDP1L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL3268399 | 0.81 | JAK2 (0.53) | GAALTA4HTDP1L3MBTL1CYP4F2 | |
| SCHEMBL27921658 | 0.81 | LMNA (0.59) | TDP1L3MBTL1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL8158041 | 0.80 | PPARG (0.58) | LTA4HTDP1L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL8162740 | 0.80 | GAA (0.56) | GAATDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2987183 | 0.79 | CYP1A2 (0.58) | LTA4HTDP1L3MBTL1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511477-B1 | Indole derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5239083-A | Anticarcinogenic agents, prostate cancer treatment | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0511477-A1 | Indole derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |