Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | GCKR | Q14397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173806 | 0.80 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL8006677 | 0.80 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6176528 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL9727631 | 0.74 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6176491 | 0.73 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL8009067 | 0.73 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6177219 | 0.72 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6175393 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6177968 | 0.71 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6175342 | 0.71 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708769-A1 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITY | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002590-A2 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITIES | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-26 | — | — | WO | disclosed |