Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.51 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7211521 | 0.99 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9035031 | 0.87 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7212562 | 0.86 | SIGMAR1 (0.59) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14825799 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2ASETD7 | |
| SCHEMBL20804357 | 0.78 | SIGMAR1 (0.90) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28186295 | 0.78 | SIGMAR1 (0.90) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14825800 | 0.77 | CYP2D6 (0.59) | ALDH1A1KDM4EMEN1KMT2ASETD7 | |
| SCHEMBL667100 | 0.76 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8112987 | 0.76 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14076364 | 0.76 | SIGMAR1 (0.79) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |