Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.50 |
| ▸ | HTR1D | P28221 | 7/20 | 0.46 |
| ▸ | HTR1B | P28222 | 5/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033135 | 0.95 | CCR2 (0.49) | CCR2 | |
| SCHEMBL9034903 | 0.92 | CCR2 (0.53) | CCR2DRD2 | |
| SCHEMBL9035493 | 0.91 | CCR2 (0.49) | CCR2HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL9035552 | 0.89 | KCNH2 (0.49) | CCR2HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL9034447 | 0.88 | ADRA1D (0.50) | CCR2HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL9033599 | 0.88 | CCR2 (0.47) | CCR2DRD2 | |
| SCHEMBL9035662 | 0.88 | CCR2 (0.48) | CCR2DRD2 | |
| SCHEMBL9035279 | 0.88 | CCR2 (0.46) | CCR2HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL9035293 | 0.87 | CCR2 (0.49) | CCR2HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL8878418 | 0.86 | CCR2 (0.56) | CCR2DRD2OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |