Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035277 | 0.86 | HTR1A (0.52) | HTR1AADRA1BADRA1A | |
| Bromide SCHEMBL9037158 | 0.85 | HTR1A (0.52) | HTR1AADRA1BADRA1A | |
| SCHEMBL9034117 | 0.83 | HTR1A (0.58) | HTR1AADRA1BADRA1A | |
| Hydrochloric Acid SCHEMBL9043516 | 0.82 | HTR1A (0.57) | HTR1AADRA1BADRA1A | |
| SCHEMBL9035223 | 0.82 | HTR1A (0.57) | HTR1AADRA1BADRA1A | |
| Hydrochloric Acid SCHEMBL9036002 | 0.81 | HTR1A (0.56) | HTR1AADRA1BADRA1A | |
| SCHEMBL9037672 | 0.81 | HTR1A (0.56) | HTR1AADRA1BADRA1A | |
| SCHEMBL9035193 | 0.78 | HTR1A (0.47) | HTR1AADRA1A | |
| SCHEMBL9458072 | 0.76 | HTR1A (0.54) | HTR1AADRA1BADRA1A | |
| SCHEMBL9036829 | 0.76 | HTR1A (0.47) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422134-B1 | 5-HT SELECTIVE AGENTS | ABBOTT LAB (US) | 1996-06-12 | — | — | EP | claimed |
| EP-0422134-B1 | 5-HT SELECTIVE AGENTS | ABBOTT LAB (US) | 1996-06-12 | — | — | EP | disclosed |