SCHEMBL9034904

SCHEMBL9034904

COc1c(N(OCc2ccccc2)C2CCC3(CC2)OCC(C)(C)CO3)ccnc1C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9035748 0.92 C5AR1 (0.35) PDE10A
SCHEMBL8840451 0.89 C5AR1 (0.32)
SCHEMBL8840474 0.81 C5AR1 (0.37) PDE10A
SCHEMBL9033878 0.79 KDM4E (0.34) PDE10A
SCHEMBL9034028 0.79 USP2 (0.34)
SCHEMBL9033980 0.76
SCHEMBL9032962 0.75 USP2 (0.31)
SCHEMBL9033920 0.74 TP53 (0.35)
SCHEMBL8840595 0.72 SLC6A5 (0.31)
SCHEMBL9034469 0.71 MAOA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719256-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
WO-1995007891-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed