SCHEMBL8840595

SCHEMBL8840595

COCc1nccc(N(OCc2ccccc2)C2CCC3(CCCCC3)CC2)c1OC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8840474 0.86 C5AR1 (0.37)
SCHEMBL8840451 0.83 C5AR1 (0.32)
SCHEMBL8840417 0.83 GRM2 (0.34)
SCHEMBL8840584 0.83 DRD3 (0.32)
SCHEMBL8840430 0.82 KMT2A (0.33)
SCHEMBL9034971 0.82
SCHEMBL8840454 0.78 TP53 (0.34)
SCHEMBL8840422 0.77 OPRM1 (0.34) SLC6A5
SCHEMBL8840444 0.77 SLC6A5 (0.32) SLC6A5
SCHEMBL8840423 0.77 HRH3 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650417-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-07-22 US disclosed
EP-0719255-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
WO-1995007890-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed