Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25219752 | 0.83 | CA1 (0.44) | CA1CA2CA9ALDH1A1TRPV1 | |
| SCHEMBL9035478 | 0.83 | ALDH1A1 (0.50) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL13802159 | 0.83 | ACHE (0.41) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL9165045 | 0.81 | NFE2L2 (0.39) | MAPTALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL3496791 | 0.81 | PPARA (0.53) | MAPTALDH1A1MAPK1HPGDSMN1; SMN2 | |
| SCHEMBL1889507 | 0.81 | MEN1 (0.39) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL6210928 | 0.80 | CA4 (0.39) | MAPTALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL9035577 | 0.78 | ALDH1A1 (0.45) | MAPTALDH1A1SMN1; SMN2LMNAEPHX2 | |
| SCHEMBL8886592 | 0.78 | NQO1 (0.54) | CA1CA2CA9ALDH1A1NPC1 | |
| SCHEMBL18365227 | 0.78 | CA1 (0.43) | CA1CA2CA9MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396698-A1 | MANUFACTURE OF ARYLOXYALDEHYDES. | ICI PLC (GB) | 1990-11-14 | — | — | EP | claimed |
| WO-1990004580-A1 | ARYLOXYALDEHYDES AND THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-03 | — | — | WO | claimed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| US-5169974-A | Process for manufacturing aryloxyaldehydes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-08 | — | — | US | disclosed |
| EP-0396698-A1 | MANUFACTURE OF ARYLOXYALDEHYDES. | ICI PLC (GB) | 1990-11-14 | — | — | EP | disclosed |
| WO-1990004580-A1 | ARYLOXYALDEHYDES AND THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-03 | — | — | WO | disclosed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | disclosed |