Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035190 | 0.81 | PARP1 (0.41) | KDM4EPARP1MEN1KMT2AHPGD | |
| SCHEMBL8824093 | 0.79 | PARP1 (0.55) | KDM4ERECQLPARP1HPGDNPSR1 | |
| SCHEMBL9243355 | 0.79 | PARP1 (0.55) | KDM4ERECQLPARP1HPGDNPSR1 | |
| SCHEMBL8823994 | 0.73 | PARP1 (0.58) | KDM4ERECQLPARP1MEN1KMT2A | |
| SCHEMBL8823991 | 0.73 | PARP1 (0.58) | KDM4ERECQLPARP1MEN1KMT2A | |
| SCHEMBL8824089 | 0.68 | PARP1 (0.45) | KDM4ERECQLPARP1 | |
| SCHEMBL8824092 | 0.68 | PARP1 (0.45) | KDM4ERECQLPARP1 | |
| SCHEMBL8824032 | 0.67 | PARP1 (0.42) | KDM4ERECQLPARP1LMNA | |
| SCHEMBL8824082 | 0.66 | PARP1 (0.47) | KDM4ERECQLPARP1LMNA | |
| SCHEMBL8824085 | 0.66 | PARP1 (0.47) | KDM4ERECQLPARP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405442-B1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARM CO LTD (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5151431-A | Diuretics | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0405442-A1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |