Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139876 | 0.84 | OPRM1 (0.40) | OPRM1KDM4EMEN1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL4835639 | 0.82 | OPRM1 (0.43) | OPRM1KDM4EMEN1ALDH1A1POLB | |
| SCHEMBL1305076 | 0.76 | MEN1 (0.32) | MEN1KMT2A | |
| Acetonitrile SCHEMBL7030137 | 0.74 | GAA (0.34) | KDM4EALDH1A1HTTHSD11B1 | |
| SCHEMBL68353 | 0.73 | — | — | |
| SCHEMBL11028940 | 0.73 | MAOA (0.40) | ALDH1A1 | |
| SCHEMBL18339382 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL2171904 | 0.71 | — | — | |
| Fluoride SCHEMBL22283858 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL28742553 | 0.71 | MAOA (0.39) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711292-A1 | AZA SPIRO COMPOUNDS ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY | KOSMIN, Gerald, Emmanuel (GB) | 1996-05-15 | — | — | EP | disclosed |