Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035501 | 0.84 | DRD3 (0.50) | HTR1AALDH1A1HTR7KDM4EDRD2 | |
| Hydrochloric Acid SCHEMBL9034412 | 0.83 | HTR1A (0.47) | HTR1AHTR7MEN1ADRA1DADRA1A | |
| SCHEMBL9035189 | 0.83 | HTR1A (0.52) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL9034117 | 0.81 | HTR1A (0.58) | HTR1AALDH1A1MEN1CYP3A4ADRA1D | |
| SCHEMBL9035223 | 0.80 | HTR1A (0.57) | HTR1AALDH1A1MEN1CYP3A4ADRA1D | |
| Hydrochloric Acid SCHEMBL9043516 | 0.80 | HTR1A (0.57) | HTR1AALDH1A1MEN1CYP3A4ADRA1D | |
| Hydrochloric Acid SCHEMBL9036002 | 0.79 | HTR1A (0.56) | HTR1AALDH1A1MEN1CYP3A4ADRA1D | |
| SCHEMBL9037672 | 0.79 | HTR1A (0.56) | HTR1AALDH1A1MEN1CYP3A4ADRA1D | |
| Hydrochloric Acid SCHEMBL9037058 | 0.78 | HTR1A (0.54) | HTR1ADRD2 | |
| SCHEMBL3886553 | 0.78 | HTR1A (0.58) | HTR1AALDH1A1HTR7KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422134-B1 | 5-HT SELECTIVE AGENTS | ABBOTT LAB (US) | 1996-06-12 | — | — | EP | claimed |
| EP-0422134-B1 | 5-HT SELECTIVE AGENTS | ABBOTT LAB (US) | 1996-06-12 | — | — | EP | disclosed |