Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.68 |
| ▸ | MAOB | P27338 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.51 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28011530 | 0.85 | MAPK1 (0.64) | MAOBTDP1MAPK1LMNAGPR132 | |
| SCHEMBL7323498 | 0.84 | MAOA (0.74) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL7865894 | 0.84 | MAPK1 (0.56) | RAB9ATDP1MAPK1ALDH1A1LMNA | |
| SCHEMBL8020581 | 0.82 | ALDH1A1 (0.74) | ALDH1A1LMNATHRBSMN1; SMN2CCNB2 | |
| SCHEMBL8020587 | 0.82 | ALDH1A1 (0.74) | ALDH1A1LMNATHRBSMN1; SMN2CCNB2 | |
| SCHEMBL314161 | 0.82 | MAOB (1.00) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL29454637 | 0.82 | MAOB (1.00) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL18002137 | 0.79 | PTPN1 (0.45) | MAOAMAOBMAPK1ALDH1A1LMNA | |
| SCHEMBL22964344 | 0.79 | MAPK1 (0.58) | MAPK1GPR132 | |
| SCHEMBL22964151 | 0.78 | MAPK1 (0.54) | MAPK1GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230406829-A1 | Heterocyclic Compound and Preparation Method and Use Thereof | SYNTRON (JIANGSU) PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-12-21 | — | — | US | disclosed |
| CN-112321513-B | Heterocyclic compound and preparation method and application thereof | 药康众拓(江苏)医药科技有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-112321513-A | Heterocyclic compound and preparation method and application thereof | 中国药科大学 | 2021-02-05 | — | — | CN | disclosed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230406829-A1 | Heterocyclic Compound and Preparation Method and Use Thereof | PDCD1, CD274, PDCD1LG2 | MAOA 2641/4885MAOB 3125/4885NPC1 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.